Nashua is a city in Hillsborough County, New Hampshire, United States. As of the 2010 census, Nashua had a total population of 86,494, making it the second-largest city in the state after Manchester. As of 2016 the population had risen to an estimated 87,882.Built around the now-departed textile industry, in recent decades it has been swept up in southern New Hampshire's economic expansion as part of the Boston region. Nashua was twice named "Best Place to Live in America" in annual surveys by Money magazine. It is the only city to get the No. 1 ranking on two occasions—in 1987 and 1998.