Milford is a town in Worcester County, Massachusetts, United States. The population was 27,999 according to the 2010 census. First settled in 1662 and incorporated in 1780, Milford became a booming industrial and mining community in the 19th century due to its unique location which includes the nearby source of the Charles River, the Mill River, the Blackstone River watershed, and large quantities of Milford pink granite.